Healthy Weight with Glucose Control

Adults wanting to support a healthy weight, those who may have reached their goal weight and want a simple, science-backed daily routine to help maintain their results. It's may also be suited for adults in midlife who feel maintaining their weight has gotten harder over time.

Akkermansia Healthy Weight is designed to support healthy weight maintenance* — not rapid loss, restriction, or stimulation. For best results, use as part of a healthy diet and active lifestyle.

Akkermansia Healthy Weight may be suitable while on a GLP-1 medication, when transitioning off the medication — throughout the weight management journey. As always, consult your healthcare professional before starting any new supplement, especially if you're currently taking medication.

In a published clinical study, pasteurised Akkermansia MucT™ was taken daily for 12 weeks and demonstrated improved metabolic health and fat loss. A second clinical study showed that when taken daily for 24 weeks post weight loss, the Akkermansia MucT™ group had gained up to 58% less weight, reducing weight rebound.

No. Because Akkermansia Healthy Weight uses pasteurized Akkermansia (a postbiotic), it's shelf-stable at room temperature — no refrigeration required.

Akkermansia munciniphila is a keystone bacterium that makes up around 4% of the gut microbiome. High levels of this gut microbe are found in lean, healthy people. Akkermansia is considered a 'next generation' probiotic and is mentioned in over 5000 research papers. Not all Akkermansia are equal, with live being unstable and clinical research being on the pasteurised or heat-treated form.

Choosing the best Akkermansia supplement includes consideration of the specific strain used and dosage being backed by human clinical research, as well as meeting strict quality criteria in sourcing and manufacturing. Akkermansia MucT™ is the original, patented strain based on 20 years of research.

In preclinical studies and a proof-of-concept human trial,¹˒² the pasteurized form of Akkermansia muciniphila MucT™ outperformed the live strain across several measures of metabolic health - supporting a stronger gut barrier, healthy blood sugar response, and healthy body composition and lipid levels. That's why we've built our formula around the pasteurised form: it's the version the science points to.​

Based on preclinical (laboratory and animal) studies and an early-stage human proof-of-concept trial. Individual results may vary.

Your gut is in constant conversation with the rest of your body. Cells lining the gut release natural messengers that help control blood sugar, signal when you're full, and support how you use energy from food³. A healthy gut lining also works as a protective barrier, keeping unwanted substances like bacterial molecules where they belong. When that barrier weakens and your gut bacteria fall out of balance, it can trigger inflammation⁴. Over time, this "low-grade inflammation" may affect how well your body handles blood sugar and fat — which is why gut health and metabolic health are so closely linked⁵.

Yes, see references below:
[1] Depommier C, Everard A, Druart C, et al. Supplementation with Akkermansia muciniphila inoverweight and obese human volunteers: a proof-of-concept exploratory study. Nature Medicine.2019;25(7):1096–1103. doi:10.1038/s41591-019-0495-2​

[2] Plovier H, Everard A, Druart C, et al. A purified membrane protein from Akkermansia muciniphilaor the pasteurized bacterium improves metabolism in obese and diabetic mice. Nature Medicine.2017;23(1):107–113. doi:10.1038/nm.4236​

[3] Gribble FM, Reimann F. The Enteroendocrine System in Obesity. Handb Exp Pharmacol. 2022;274:109–129. PMID: 35419621. https://pubmed.ncbi.nlm.nih.gov/35419621/​

[4] Winer DA, Luck H, Tsai S, Winer S. The Intestinal Immune System in Obesity and Insulin Resistance. Cell Metab. 2016;23(3):413–426. PMID: 28045403. https://pubmed.ncbi.nlm.nih.gov/28045403/​

[5] Cani PD, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes. 2007;56(7):1761–1772. PMID: 17456850. https://pubmed.ncbi.nlm.nih.gov/17456850/​